Steroid sulfatase

STS
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 1P49
Identifiers
Aliases	STS, ARSC, ARSC2, ARSC1, ASC, ES, SSDD, XLI, Steroid sulfatase (microsomal), isozyme S, steroid sulfatase
External IDs	OMIM: 300747; HomoloGene: 47918; GeneCards: STS; OMA:STS - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp22.31 Start 7,147,237 bp[1] End 7,804,358 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta endothelial cell palpebral conjunctiva Brodmann area 23 pancreatic ductal cell decidua lateral nuclear group of thalamus middle temporal gyrus primary visual cortex Brodmann area 46 n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding catalytic activity steryl-sulfatase activity sulfuric ester hydrolase activity hydrolase activity arylsulfatase activity Cellular component integral component of membrane endosome Golgi apparatus endoplasmic reticulum lumen membrane endoplasmic reticulum membrane plasma membrane endoplasmic reticulum lysosome intracellular membrane-bounded organelle Biological process steroid metabolic process glycosphingolipid metabolic process lipid metabolism female pregnancy steroid catabolic process epidermis development metabolism Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 412 n/a Ensembl ENSG00000101846 n/a UniProt P08842 n/a RefSeq (mRNA) NM_000351 NM_001320750 NM_001320751 NM_001320752 NM_001320753 NM_001320754 n/a RefSeq (protein) NP_000342 NP_001307679 NP_001307680 NP_001307681 NP_001307682 NP_001307683 n/a Location (UCSC) Chr X: 7.15 – 7.8 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Steroid sulfatase (STS), or steryl-sulfatase (EC 3.1.6.2), formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene.^[3]