Back بنية وجينوم فيروس الإيدز Arabic Struktur dan genom HIV ID HIV의 유전체와 구조 Korean എച്ച്.ഐ.വി.യുടെ ഘടനയും ജീനോമും Malayalam Estrutura e genoma do VIH Portuguese Будова ВІЛ Ukrainian Cấu trúc và bộ gen của HIV Vietnamese
The genome and proteins of HIV (human immunodeficiency virus) have been the subject of extensive research since the discovery of the virus in 1983.[1][2] "In the search for the causative agent, it was initially believed that the virus was a form of the Human T-cell leukemia virus (HTLV), which was known at the time to affect the human immune system and cause certain leukemias. However, researchers at the Pasteur Institute in Paris isolated a previously unknown and genetically distinct retrovirus in patients with AIDS which was later named HIV."[3] Each virion comprises a viral envelope and associated matrix enclosing a capsid, which itself encloses two copies of the single-stranded RNA genome and several enzymes. The discovery of the virus itself occurred two years following the report of the first major cases of AIDS-associated illnesses.[4][5]
- ^ Barré-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, Dauguet C, Axler-Blin C, Vézinet-Brun F, Rouzioux C, Rozenbaum W, Montagnier L (May 1983). "Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)". Science. 220 (4599): 868–71. Bibcode:1983Sci...220..868B. doi:10.1126/science.6189183. PMID 6189183. S2CID 390173.
- ^ Gallo RC, Sarin PS, Gelmann EP, Robert-Guroff M, Richardson E, Kalyanaraman VS, Mann D, Sidhu GD, Stahl RE, Zolla-Pazner S, Leibowitch J, Popovic M (May 1983). "Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS)". Science. 220 (4599): 865–7. Bibcode:1983Sci...220..865G. doi:10.1126/science.6601823. PMID 6601823.
- ^ Churi C, Ross MW (2015). "Hiv/Aids". In Whelehan P, Bolin A (eds.). The international encyclopedia of human sexuality. Wiley. ISBN 9781405190060. OCLC 949701914.
- ^ Centers for Disease Control (June 1981). "Pneumocystis pneumonia--Los Angeles". MMWR. Morbidity and Mortality Weekly Report. 30 (21): 250–2. PMID 6265753.
- ^ Centers for Disease Control (CDC) (July 1981). "Kaposi's sarcoma and Pneumocystis pneumonia among homosexual men--New York City and California" (PDF). MMWR. Morbidity and Mortality Weekly Report. 30 (25): 305–8. PMID 6789108. Archived from the original on October 22, 2012. Retrieved September 15, 2017.
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