Sultiame

Sultiame
Clinical data
Trade namesOspolot
Other namesSulthiame (AAN AU), sulthiame (USAN US)
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • AU: D
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
Pharmacokinetic data
Bioavailability100% (oral)
Protein binding29%
MetabolismHepatic secretion
Elimination half-life24 hours
ExcretionFecal (10%) and renal (90%)
Identifiers
  • 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.465 Edit this at Wikidata
Chemical and physical data
FormulaC10H14N2O4S2
Molar mass290.35 g·mol−1
3D model (JSmol)
  • O=S2(=O)N(c1ccc(cc1)S(=O)(=O)N)CCCC2
  • InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16) checkY
  • Key:HMHVCUVYZFYAJI-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Sultiame (or sulthiame) is a sulfonamide and inhibitor of the enzyme carbonic anhydrase. It is used as an anticonvulsant.


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