Surface epithelial-stromal tumor

Surface epithelial-stromal tumor
High magnification micrograph of a Brenner tumor, a type of surface epithelial-stromal tumor. H&E stain.
SpecialtyOncology

Surface epithelial-stromal tumors are a class of ovarian neoplasms that may be benign or malignant. Neoplasms in this group are thought to be derived from the ovarian surface epithelium (modified peritoneum) or from ectopic endometrial or fallopian tube (tubal) tissue. Tumors of this type are also called ovarian adenocarcinoma.[1] This group of tumors accounts for 90% to 95% of all cases of ovarian cancer; however is mainly only found in postmenopausal women with the exception of the United States where 7% of cases occur in women under the age of 40.[2][3][4][5][6][7] Serum CA-125 is often elevated but is only 50% accurate so it is not a useful tumor marker to assess the progress of treatment. 75% of women with epithelial ovarian cancer are found within the advanced-stages; however younger patients are more likely to have better prognoses than older patients.[8][9][10][11] [12]

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  2. ^ Centers for Disease Control and Prevention, CDC WONDER. United States and Puerto Rico cancer statistics, 1999–2013 inci- dence incidence request.Available at: http://wonder.cdc.gov/ cancer-v2013.html. Retrieved December 1, 2016.
  3. ^ Kashima K, Yahata T, Fujita K, Tanaka K. Outcomes of fertility-sparing surgery for women of reproductive age with FIGO stage IC epithelial ovarian cancer. Int J Gynaecol Obstet 2013;121:53–5.
  4. ^ Rauh-Hain JA, Foley O, Winograd D, Andrade C, Clark RM, Vargas RJ, et al. Clinical characteristics and outcomes of pa- tients with stage I epithelial ovarian cancer compared to fallo- pian tube cancer. Am J Obstet Gynecol 2015;212:600.e1–8.
  5. ^ Wright JD, Shah M, Mathew L, Burke WM, Culhane J, Gold- man N, et al. Fertility preservation in young women with epi- thelial ovarian cancer. Cancer 2009;115:4118–26.
  6. ^ Melamed A., Rizzo A.E., Nitecki R., et al All-cause mortality after fertility-sparing surgery for stage i epithelial ovarian cancer. Obstet. Gynecol.. 2017;130(1):71-79. doi:10.1097/AOG.0000000000002102
  7. ^ Bradshaw KD, Schorge JO, Schaffer J, Lisa M H, Hoffman BG (2008). Williams' Gynecology. McGraw-Hill Professional. ISBN 978-0-07-147257-9.
  8. ^ Smedley H, Sikora K. Age as a prognostic factor in epithelial ovarian carcinoma. Br J Obstet Gynaecol 2016;92:839–42.
  9. ^ Ghezzi F, Cromi A, Fanfani F, Malzoni M, Ditto A, De Iaco P, et al. Laparoscopic fertility-sparing surgery for early ovarian epithelial cancer: a multi-institutional experience. Gynecol On- col 2016;141:461–5.
  10. ^ Melamed A, Keating NL, Clemmer JT, Bregar AJ, Wright JD, Boruta DM, et al. Laparoscopic staging for apparent stage I epithelial ovarian cancer. Am J Obstet Gynecol 2017;216:50. e1–50.e12.
  11. ^ Kashima K, Yahata T, Fujita K, Tanaka K. Outcomes of fertility-sparing surgery for women of reproductive age with FIGO stage IC epithelial ovarian cancer. Int J Gynaecol Obstet 2013;121:53–5.
  12. ^ Melamed A., Rizzo A.E., Nitecki R., et al All-cause mortality after fertility-sparing surgery for stage i epithelial ovarian cancer. Obstet. Gynecol.. 2017;130(1):71-79. doi:10.1097/AOG.0000000000002102

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