Tandospirone

Tandospirone
Clinical data
Trade names	Sediel
Other names	Metanopirone
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Metabolites	1-PPTooltip 1-(2-Pyrimidinyl)piperazine
Elimination half-life	Tandospirone: 2–3 hours; 1-PPTooltip 1-(2-Pyrimidinyl)piperazine: 3–5 hours
Excretion	Urine (70%; 0.1% as unchanged drug)
Identifiers
	IUPAC name (1R,2R,6S,7S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-4-azatricyclo[5.2.1.02,6]decane-3,5-dione;
CAS Number	87760-53-0 ;
PubChem CID	91273;
IUPHAR/BPS	55;
ChemSpider	82421 ;
UNII	190230I669;
ChEBI	CHEBI:145673;
ChEMBL	ChEMBL274047 ;
CompTox Dashboard (EPA)	DTXSID6048836 ;
ECHA InfoCard	100.210.461
Chemical and physical data
Formula	C21H29N5O2
Molar mass	383.496 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1N(C(=O)[C@H]3[C@@H]1[C@@H]2CC[C@H]3C2)CCCCN5CCN(c4ncccn4)CC5;
	InChI InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18- ; Key:CEIJFEGBUDEYSX-FZDBZEDMSA-N ;
	(what is this?) (verify)

Tandospirone, sold under the brand name Sediel, is an anxiolytic and antidepressant medication used in Japan and China, where it is marketed by Dainippon Sumitomo Pharma. It is a member of the azapirone class of drugs and is closely related to other azapirones like buspirone and gepirone.

Tandospirone was introduced for medical use in Japan in 1996^[1] and in China in 2004.^[2]

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