Back أهبة التخثر Arabic Trombofilia AST Trombofília Catalan Thrombophilie German Θρομβοφιλία Greek Trombofilia Spanish Thrombophilie French קרישיות יתר HE Թրոմբոֆիլիա Armenian Trombofilia ID
| Thrombophilia | |
|---|---|
 | |
| An ultrasound image demonstrating a blood clot in the left common femoral vein. | |
| Specialty | Hematology  |
Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).[1][2] Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not provoked by other causes.[3] A significant proportion of the population has a detectable thrombophilic abnormality, but most of these develop thrombosis only in the presence of an additional risk factor.[2]
There is no specific treatment for most thrombophilias, but recurrent episodes of thrombosis may be an indication for long-term preventive anticoagulation.[2] The first major form of thrombophilia to be identified by medical science, antithrombin deficiency, was identified in 1965, while the most common abnormalities (including factor V Leiden) were described in the 1990s.[4][5]
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