Triclosan

Triclosan
Names
	Preferred IUPAC name 5-Chloro-2-(2,4-dichlorophenoxy)phenol
	Other names 2,4,4′-Trichloro-2′-hydroxydiphenyl ether; 5-Chloro-(2,4-dichlorophenoxy)phenol; Trichloro-2′-hydroxydiphenyl ether; CH-3565; Lexol 300; Irgasan DP 300; Ster-Zac
Identifiers
CAS Number	3380-34-5 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:164200 ;
ChEMBL	ChEMBL849 ;
ChemSpider	5363 ;
DrugBank	DB08604 ;
ECHA InfoCard	100.020.167
KEGG	D06226 ;
PubChem CID	5564;
UNII	4NM5039Y5X ;
CompTox Dashboard (EPA)	DTXSID5032498 ;
	InChI InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H Key: XEFQLINVKFYRCS-UHFFFAOYSA-N ; InChI=1/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H Key: XEFQLINVKFYRCS-UHFFFAOYAS;
	SMILES Clc2cc(Cl)ccc2Oc1ccc(Cl)cc1O;
Properties
Chemical formula	C12H7Cl3O2
Molar mass	289.54 g·mol−1
Appearance	White solid
Density	1.49 g/cm3
Melting point	55–57 °C (131–135 °F; 328–330 K)
Boiling point	120 °C (248 °F; 393 K)
Pharmacology
ATC code	D08AE04 (WHO) D09AA06 (WHO) (medicated dressing)
Hazards
NFPA 704 (fire diamond)	2 1 0
Flash point	162.2 °C (324.0 °F; 435.3 K)
Safety data sheet (SDS)	MSDS
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of action to triclocarban. Its efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remains controversial. Additional research seeks to understand its potential effects on organisms and environmental health.

Triclosan was developed in 1966.^[1] A 2006 study recommended showering with 2% triclosan as a regimen in surgical units to rid patients' skin of methicillin-resistant Staphylococcus aureus (MRSA).^[2]

^ Boyce JM, Pittet D, Healthcare Infection Control Practices Advisory Committee, HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force (25 October 2002). "Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America". MMWR. Recommendations and Reports. 51 (RR-16): 1–45, quiz CE1–4. PMID 12418624.
^ Coia J, Duckworth G, Edwards D, Farrington M, Fry C, Humphreys H, Mallaghan C, Tucker D, Joint Working Party of the British Society of Antimicrobial Chemotherapy, Hospital Infection S, Infection Control Nurses Association (2006). "Guidelines for the control and prevention of meticillin-resistant Staphylococcus aureus (MRSA) in healthcare facilities". Journal of Hospital Infection. 63: S1–44. doi:10.1016/j.jhin.2006.01.001. PMID 16581155.