Tubocurarine chloride

Tubocurarine chloride
Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a682860
Pregnancy; category	AU: C; ;
Routes of; administration	IV
ATC code	M03AA02 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Bioavailability	100% (IV)
Protein binding	50%
Elimination half-life	1–2 hours
Identifiers
	IUPAC name 6,6′-dimethoxy-2,2′,2′-trimethyltubocuraran-2,2′-diium-7′,12′-diol;
CAS Number	6989-98-6 ;
PubChem CID	6000;
IUPHAR/BPS	2294;
DrugBank	DB01199 ;
ChemSpider	5778 ;
UNII	900961Z8VR;
ChEBI	CHEBI:9774 ;
ChEMBL	ChEMBL1687 ;
CompTox Dashboard (EPA)	DTXSID0048393 ;
Chemical and physical data
Formula	C37H42Cl2N2O6
Molar mass	681.65 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Oc7ccc1cc7Oc5cc6[C@H](Cc4ccc(Oc2c3[C@@H](C1)[N+](C)(C)CCc3cc(OC)c2O)cc4)[N+](C)(C)CCc6cc5OC;
	InChI InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41)/p+1/t28-,29+/m0/s1 ; Key:JFJZZMVDLULRGK-URLMMPGGSA-O ;
	(what is this?) (verify)

Tubocurarine (also known as d-tubocurarine or DTC) is a toxic benzylisoquinoline alkaloid historically known for its use as an arrow poison. In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation. Safer alternatives, such as cisatracurium and rocuronium, have largely replaced it as an adjunct for clinical anesthesia and it is now rarely used.