U.S. Route 150 (US 150) in Indiana is a 176.315-mile-long (283.751 km) east–west highway that travels from the Illinois state line east of Paris, Illinois to Louisville, Kentucky at the Kentucky state line. A section of US 150 from New Goshen to Vincennes travels north–south instead of east–west. US 150 travels concurrently with its parent route, US 50, from Vincennes to Shoals. Between West Terre Haute and Terre Haute, US 150 travels along part of the historic National Road. Also, from Vincennes to New Albany, the route is designated as part of Indiana's Historic Pathways, as it roughly parallels what was then part of the Buffalo Trace.
^Indiana Department of Transportation (July 2016). Reference Post Book(PDF). Indianapolis: Indiana Department of Transportation.