US 278 highlighted in red | |
Route information | |
Auxiliary route of US 78 | |
Length | 1,074 mi[citation needed] (1,728 km) |
Existed | 1952–present |
Major junctions | |
West end | ![]() ![]() |
| |
East end | ![]() ![]() |
Location | |
Country | United States |
States | Arkansas, Mississippi, Alabama, Georgia, South Carolina |
Highway system | |
U.S. Route 278 (US 278) is a parallel route of US 78. It currently runs for 1,074 miles (1,728 km) from Hilton Head Island, South Carolina, to Wickes, Arkansas at US 71/US 59, passing through five states in the process. Landmarks along its route include the Department of Energy's Savannah River Site in South Carolina and the Tennessee-Tombigbee Waterway in eastern Mississippi. There are several universities located along the highway including Georgia State University, the University of Mississippi, and the University of Arkansas at Monticello.