U.S. Route 421 in Virginia

U.S. Route 421
U.S. Route 421
	US 421 highlighted in red
Route information
	Maintained by VDOT
Length	69.23 mi (111.41 km)
Existed	ca. 1950–present
Tourist; routes	Virginia Byway
Major junctions
South end	US 421 / SR 34 in Bristol
	US 11 / US 11E / US 19 / SR 381 in Bristol; US 11W / SR 1 in Bristol; I-81 / US 58 in Bristol; SR 224 near Weber City; US 23 in Weber City; SR 65 in Clinchport; US 58 at Dot; ; US 58 Alt. in Pennington Gap; SR 352 near St. Charles;
North end	US 421 near St. Charles
Location
Country	United States
State	Virginia
Counties	City of Bristol, Washington, Scott, Lee
Highway system
	United States Numbered Highway System; List; Special; Divided; Virginia Routes; Interstate; US; Primary; Secondary; Byways; History; HOT lanes;

U.S. Route 421 (US 421) is a part of the U.S. Highway System that runs from Fort Fisher, North Carolina to Michigan City, Indiana. In Virginia, the U.S. Highway runs 69.23 miles (111.41 km) from the Tennessee state line between the twin cities of Bristol, Tennessee and Bristol, Virginia north and west to the Kentucky state line near St. Charles. Between its endpoints, US 421 has lengthy concurrencies with US 23 and US 58 during its course through Bristol, Weber City, Gate City, Duffield, and Pennington Gap in Southwest Virginia.

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