Tetraziklina |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/1/15/Tetracycline_skeletal.svg/190px-Tetracycline_skeletal.svg.png) |
Formula kimikoa | C22H24N2O8 |
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SMILES kanonikoa | 2D eredua |
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SMILES isomerikoa | C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O |
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MolView | 3D eredua |
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Aurkitzailea | Lloyd Conover (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Mota | Achromycin (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Tautomeroa | (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboximidic acid (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Masa molekularra | 444,1533 Da |
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Konposatu aktiboa | Achromycin V (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Tratatzen du | Klamidiasi, akne, rickettsiosi, Gonorrea, bronkitis akutu, gram-negative bacterial infection (en) eta peripheral vascular disease (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Interakzioak | Warfarina, tretinoin (en) , acitretin (en) eta isotretinoin (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Haurdunaldia | Australian pregnancy category D (en) eta US pregnancy category D (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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Rola | protein synthesis inhibitor (en) , Bakterio-kontrako, farmako esentzial, tetracycline antibiotic (en) , Bakterizida eta developmental toxicant (en) ![Itzuli](//upload.wikimedia.org/wikipedia/commons/thumb/7/70/Noun_Project_label_icon_1116097_cc_mirror.svg/10px-Noun_Project_label_icon_1116097_cc_mirror.svg.png) |
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InChlKey | NWXMGUDVXFXRIG-WESIUVDSSA-N |
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CAS zenbakia | 60-54-8 |
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ChemSpider | 10257122 |
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PubChem | 54675776 eta 51580080 |
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Reaxys | 2230417 |
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Gmelin | 27902 |
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ChEBI | 1103368 |
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ChEMBL | CHEMBL1440 |
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EC zenbakia | 200-481-9 |
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ECHA | 100.000.438 |
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MeSH | D013752 |
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RxNorm | 10395 |
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KNApSAcK | C00062381 |
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UNII | F8VB5M810T |
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NDF-RT | N0000146005 |
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KEGG | D00201 |
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PDB Ligand | TAC |
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Tetraziklinak espektro zabaleko antibiotikoak dira, gehienak era sintetikoan lortutakoak. Familia honi izena ematen dion antibiotikoa, tetraziklina bera, Streptomyces aureofassiens bakterioak sortzen du era naturalean.
Tetraziklina guztien egitura kimikoa ziklikoa da (irudia).