Nitrat reduktaza (hinon) (EC 1.7.5.1, nitratna reduktaza A, nitratna reduktaza Z, hinol/nitratna oksidoreduktaza, hinol-nitratna oksidoreduktaza, hinol:nitrat oksidoreduktaza, NarA, NarZ, NarGHI) je enzim sa sistematskim imenom nitrit:hinon oksidoreduktaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- nitrat + hinol nitrit + hinon +H2O
Ovaj za membranu vezani enzim učestvuje u anaerobnoj respiraciji.
- ↑ Enoch, H.G. and Lester, R.L. (1974). „The role of a novel cytochrome b-containing nitrate reductase and quinone in the in vitro reconstruction of formate-nitrate reductase activity of E. coli”. Biochem. Biophys. Res. Commun. 61: 1234-1241. PMID 4616697.
- ↑ Bertero, M.G., Rothery, R.A., Palak, M., Hou, C., Lim, D., Blasco, F., Weiner, J.H. and Strynadka, N.C. (2003). „Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A”. Nat. Struct. Biol. 10: 681-687. PMID 12910261.
- ↑ Lanciano, P., Magalon, A., Bertrand, P., Guigliarelli, B. and Grimaldi, S. (2007). „High-stability semiquinone intermediate in nitrate reductase A (NarGHI) from Escherichia coli is located in a quinol oxidation site close to heme bD”. Biochemistry 46: 5323-5329. PMID 17439244.
- ↑ Bertero, M.G., Rothery, R.A., Boroumand, N., Palak, M., Blasco, F., Ginet, N., Weiner, J.H. and Strynadka, N.C. (2005). „Structural and biochemical characterization of a quinol binding site of Escherichia coli nitrate reductase A”. J. Biol. Chem. 280: 14836-14843. PMID 15615728.
- ↑ Bonnefoy, V. and Demoss, J.A. (1994). „Nitrate reductases in Escherichia coli”. Antonie Van Leeuwenhoek 66: 47-56. PMID 7747940.
- ↑ Guigliarelli, B., Asso, M., More, C., Augier, V., Blasco, F., Pommier, J., Giordano, G. and Bertrand, P. (1992). „EPR and redox characterization of iron-sulfur centers in nitrate reductases A and Z from Escherichia coli. Evidence for a high-potential and a low-potential class and their relevance in the electron-transfer mechanism”. Eur. J. Biochem. 207: 61-68. PMID 1321049.
- ↑ Iobbi-Nivol, C., Santini, C.L., Blasco, F. and Giordano, G. (1990). „Purification and further characterization of the second nitrate reductase of Escherichia coli K12”. Eur. J. Biochem. 188: 679-687. PMID 2139607.