Prostaciklin

Prostaciklin

(IUPAC) ime
(Z)-5-[(4R,5R)-5-hydroxy-4-((S,E)-3-hydroxyoct-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid
Klinički podaci
Identifikatori
CAS broj	35121-78-9
ATC kod	B01AC09
PubChem[1][2]	114805
DrugBank	APRD00949
ChEMBL[3]	CHEMBL962 Y
Hemijski podaci
Formula	C20H32O5
Mol. masa	352.465 g/mol
SMILES	eMolekuli & PubHem
InChI InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 Y Key: KAQKFAOMNZTLHT-OZUDYXHBSA-N Y
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Prostaciklin (PGI₂) je član familije lipidnih molekula poznatih kao eikozanoidi.

Kao lek, on je takođe poznat kao "epoprostenol". Ovi termini često imaju sinonimno značenje.^[4]

1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
3. ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
4. ↑ Kermode J, Butt W, Shann F (August 1991). „Comparison between prostaglandin E1 and epoprostenol (prostacyclin) in infants after heart surgery”. British heart journal 66 (2): 175–8. DOI:10.1136/hrt.66.2.175. PMC 1024613. PMID 1883670.